Description

6-Fluoro-3-Iodo-4-(1H)Indazole Carboxylic Acid is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is critical for research and development in pharmaceutical chemistry, where its unique halogenated indazole core enables the creation of novel bioactive molecules. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile functional groups.
• Agrochemical Development: Serves as a building block for novel herbicides and fungicides with specific modes of action.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses producing complex, high-value compounds for clients.
• Academic Research: Used in university and institutional labs for exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	6-Fluoro-3-Iodo-4-(1H)Indazole Carboxylic Acid
CAS No.	885522-05-4
Molecular Formula	C8H4FIN2O2
Molecular Weight	305.03 g/mol
Synonyms	4-(1H-Indazole)-6-fluoro-3-iodocarboxylic Acid; 6-Fluoro-3-iodo-1H-indazole-4-carboxylic acid; 6-Fluoro-3-iodo-4-carboxyindazole; 885522-05-4; 3-Iodo-6-fluoro-1H-indazole-4-carboxylic acid; 4-Carboxy-6-fluoro-3-iodoindazole; 6-Fluoro-3-iodoindazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 6-Fluoro-3-Iodo-4-(1H)Indazole Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.