Description

3-Bromo-6-Fluoro-4-Indazolecarboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and other therapeutic areas. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for constructing complex molecular architectures where precise bromo and fluoro substitution patterns are critical for bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated indazole core.
• Material Science: Serves as a precursor for functionalized ligands and monomers in specialty polymers.
• Chemical Biology: Employed as a molecular probe or tag in biochemical assay development and target identification.
• Academic & Contract Research: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting point for the preparation of more complex, tailored indazole derivatives for specific client projects.

Basic Information

Product Name	3-Bromo-6-Fluoro-4-Indazolecarboxylic Acid
CAS No.	885522-01-0
Molecular Formula	C8H4BrFN2O2
Molecular Weight	259.03 g/mol
Synonyms	3-Bromo-6-fluoro-1H-indazole-4-carboxylic acid; 6-Fluoro-3-bromo-1H-indazole-4-carboxylic acid; 4-Indazolecarboxylic acid, 3-bromo-6-fluoro-; 885522-01-0; 3-Bromo-6-fluoroindazole-4-carboxylic acid; 3-Br-6-F-4-Indazole-COOH; 6-Fluoro-3-bromoindazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Fluoro-4-Indazolecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.