Description

4-Fluoro-3-Hydroxy-6-Indazolecarboxylic Acid Methyl Ester is a high-purity fluorinated indazole derivative, a critical advanced pharmaceutical intermediate (API) for modern drug discovery. Its unique molecular scaffold, featuring both fluorine and hydroxyl substituents, makes it a versatile building block for synthesizing targeted bioactive compounds. This product is essential for R&D and production in pharmaceutical and agrochemical sectors, where precise molecular architecture is paramount for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging the bioactivity of the fluorinated indazole core.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme function and cellular signaling processes.
• Material Science: Potential building block for advanced organic electronic materials and specialty polymers due to its conjugated system.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and library production in medicinal chemistry programs.

Basic Information

Item	Detail
Product Name	4-Fluoro-3-Hydroxy-6-Indazolecarboxylic Acid Methyl Ester
CAS No.	885521-47-1
Molecular Formula	C9H7FN2O3
Molecular Weight	210.16 g/mol
Synonyms	Methyl 4-Fluoro-3-hydroxy-1H-indazole-6-carboxylate; 4-Fluoro-3-hydroxy-1H-indazole-6-carboxylic acid methyl ester; 6-Indazolecarboxylic acid, 4-fluoro-3-hydroxy-, methyl ester; 1H-Indazole-6-carboxylic acid, 4-fluoro-3-hydroxy-, methyl ester
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Hydroxy-6-Indazolecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.