Description

3-Chloro-4-Nitro-6-(1H)Indazole Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and targeted therapy research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex indazole-based drug candidates.
• Oncology Research: Used in the development of kinase inhibitors and other targeted cancer therapeutics.
• Agrochemical Development: Serves as a precursor for creating novel herbicides and pesticides with specific modes of action.
• Material Science: Potential monomer or additive for synthesizing specialized polymers and advanced organic materials.
• Biochemical Tool Compound: Used in life sciences research to study enzyme inhibition and cellular signaling pathways.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs for client-specific molecule development.

Basic Information

Product Name	3-Chloro-4-Nitro-6-(1H)Indazole Carboxylic Acid
CAS No.	885521-17-5
Molecular Formula	C8H4ClN3O4
Molecular Weight	241.59 g/mol
Synonyms	3-Chloro-4-nitro-1H-indazole-6-carboxylic acid; 6-(1H)-Indazolecarboxylic acid, 3-chloro-4-nitro-; 3-Chloro-4-nitro-6-carboxyindazole; 1H-Indazole-6-carboxylic acid, 3-chloro-4-nitro-; 885521-17-5; 3-Chloro-4-nitroindazole-6-carboxylic acid; 4-Nitro-3-chloro-1H-indazole-6-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Nitro-6-(1H)Indazole Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.