Description

3-Bromo-4-Nitro-6-(1H)Indazole Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated indazole structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for synthesizing novel, targeted therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties.
• Agrochemical Development: Serves as a building block for creating novel crop protection agents with specific modes of action.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and cellular signaling processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP or research-grade conditions.

Basic Information

Product Name	3-Bromo-4-Nitro-6-(1H)Indazole Carboxylic Acid
CAS No.	885521-11-9
Molecular Formula	C8H4BrN3O4
Molecular Weight	286.04 g/mol
Synonyms	6-(1H)-Indazolecarboxylic acid, 3-bromo-4-nitro-; 3-Bromo-4-nitro-1H-indazole-6-carboxylic acid; 3-Bromo-4-nitro-6-carboxyindazole; 885521-11-9; 3-Br-4-NO2-6-(1H)-Indazole-COOH; 4-Nitro-3-bromo-1H-indazole-6-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Nitro-6-(1H)Indazole Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.