Description

6-Bromo-4-Fluoro-3-(1H)Indazole Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique halogenated indazole core structure makes it a critical intermediate for the development of novel pharmacologically active compounds. This product is primarily utilized by pharmaceutical R&D and fine chemical manufacturers seeking to incorporate complex, halogen-substituted heterocycles into their molecular libraries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates targeting various therapeutic areas, including oncology and central nervous system (CNS) disorders.
• Kinase Inhibitor Development: Serves as a privileged scaffold for constructing potent and selective kinase inhibitors due to the indazole pharmacophore.
• Agrochemical Research: Used in the discovery of new active ingredients for crop protection, leveraging its halogenated aromatic system.
• Material Science: Potential building block for advanced organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology: Employed as a probe or linker in the development of chemical tools for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and complex APIs on a commercial scale.

Basic Information

Product Name	6-Bromo-4-Fluoro-3-(1H)Indazole Carboxylic Acid
CAS No.	885520-62-7
Molecular Formula	C8H4BrFN2O2
Molecular Weight	259.03 g/mol
Synonyms	6-Bromo-4-fluoro-1H-indazole-3-carboxylic acid; 4-Fluoro-6-bromo-1H-indazole-3-carboxylic acid; 6-Bromo-4-fluoroindazole-3-carboxylic acid; 3-Carboxy-6-bromo-4-fluoroindazole; 1H-Indazole-3-carboxylic acid, 6-bromo-4-fluoro-; 885520-62-7; 6-Br-4-F-3-indazole-COOH
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Fluoro-3-(1H)Indazole Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 97.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.