Description

1H-Indole, 6-Iodo-4-Nitro- CAS NO 885520-55-8 is a high-purity, halogenated nitroindole derivative, a crucial advanced intermediate for synthesizing complex organic molecules. Its unique structure, featuring both iodine and nitro substituents, makes it a versatile building block for introducing specific functional groups and enabling key coupling reactions in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working in medicinal chemistry, material science, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and CNS (Central Nervous System) research.
• Agrochemical Development: Used to create new active ingredients for crop protection products, leveraging its halogenated indole core.
• Material Science Research: Serves as a building block for organic electronic materials, dyes, and photoactive compounds.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological systems.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki-Miyaura and Sonogashira couplings.
• Academic & Industrial R&D: Fundamental research tool in synthetic organic chemistry for constructing complex heterocyclic frameworks.

Basic Information

Product Name	1H-Indole, 6-Iodo-4-Nitro-
CAS No.	885520-55-8
Molecular Formula	C8H5IN2O2
Molecular Weight	288.04 g/mol
Synonyms	6-Iodo-4-nitro-1H-indole; 4-Nitro-6-iodoindole; 6-Iodo-4-nitroindole; 1H-Indole, 6-iodo-4-nitro-; 4-Nitro-6-iodo-1H-indole; 6-Iodo-4-nitro-1H-indole; 885520-55-8
EINECS	Contact for details

Quality Control

Our 1H-Indole, 6-Iodo-4-Nitro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.