Description

4-Bromo-3-Hydroxy-1H-Indazole-6-Carboxylic Acid is a high-purity, functionalized indazole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique bromo-hydroxy-carboxylic acid substitution pattern, which enables precise molecular modifications and the construction of complex heterocyclic scaffolds. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, particularly kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indazole core.
• Chemical Biology: Employed as a molecular probe or linker in proteomics and bio-conjugation studies.
• Material Science: Serves as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Academic & Contract Research: Essential for methodological development and novel synthetic route exploration in organic chemistry laboratories.

Basic Information

Product Name	4-Bromo-3-Hydroxy-1H-Indazole-6-Carboxylic Acid
CAS No.	885520-30-9
Molecular Formula	C8H5BrN2O3
Molecular Weight	257.04 g/mol
Synonyms	4-Bromo-3-hydroxy-1H-indazole-6-carboxylic acid; 6-Carboxy-4-bromo-3-hydroxyindazole; 4-Bromo-3-hydroxyindazole-6-carboxylic acid; 1H-Indazole-6-carboxylic acid, 4-bromo-3-hydroxy-; 885520-30-9; 4-Br-3-OH-1H-indazole-6-COOH
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Hydroxy-1H-Indazole-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a Certificate of Analysis (COA) with every shipment to ensure full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.