Description

6-Amino-3-Bromo-4-Fluoro (1H)Indazole is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which incorporates reactive amino, bromo, and fluoro substituents on the indazole core, enabling precise derivatization for creating novel chemical entities. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, particularly in the development of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile functional groups for further chemical modification.
• Agrochemical Synthesis: Serves as a building block for creating new active ingredients in crop protection products.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science Research: Potential precursor for the synthesis of specialized organic materials and ligands for catalysis.

Basic Information

Product Name	6-Amino-3-Bromo-4-Fluoro (1H)Indazole
CAS No.	885520-17-2
Molecular Formula	C7H5BrFN3
Molecular Weight	230.04 g/mol
Synonyms	6-Amino-3-bromo-4-fluoro-1H-indazole; 3-Bromo-4-fluoro-1H-indazol-6-amine; 4-Fluoro-3-bromo-1H-indazol-6-amine; 1H-Indazole, 6-amino-3-bromo-4-fluoro-; 6-Amino-3-bromo-4-fluoroindazole; ABFI; 885520-17-2
EINECS	Contact for details

Quality Control

Our 6-Amino-3-Bromo-4-Fluoro (1H)Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and development applications. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data are provided to guarantee traceability and batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.