Description

4-Amino-6-Fluoroindazole is a high-purity, advanced pharmaceutical intermediate characterized by its unique indazole core structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of targeted small-molecule therapeutics. It serves as a key building block for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel bioactive compounds.

Application

4-Amino-6-Fluoroindazole is a versatile synthon used in various sophisticated chemical syntheses. Its primary and potential applications include:

• Pharmaceutical Intermediate: Core building block for the research and development of kinase inhibitors and other targeted cancer therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides with specific modes of action.
• Chemical Biology Research: Serves as a probe or scaffold in drug discovery for studying protein-ligand interactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Material Science Precursor: Potential use in the development of organic electronic materials and ligands for catalysis.

Basic Information

Product Name	4-Amino-6-Fluoroindazole
CAS No.	885520-16-1
Molecular Formula	C7H6FN3
Molecular Weight	151.14 g/mol
Synonyms	6-Fluoro-1H-indazol-4-amine; 4-Amino-6-fluoro-1H-indazole; 6-Fluoro-4-aminoindazole; 4-Amino-6-fluoroindazole; 1H-Indazol-4-amine, 6-fluoro-; AI3-52031; ZINC000103249505; AKOS005209155
EINECS	Contact for details

Quality Control

Our 4-Amino-6-Fluoroindazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.