Description

6-Amino-3-Chloro-4-Fluoro (1H)Indazole is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated indazole core.
• Chemical Biology Probe Synthesis: Serves as a versatile scaffold for creating tool compounds to study biological pathways and protein functions.
• Material Science Applications: Potential building block for advanced organic electronic materials and functional polymers.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process optimization for client projects.

Basic Information

Product Name	6-Amino-3-Chloro-4-Fluoro (1H)Indazole
CAS No.	885520-15-0
Molecular Formula	C7H5ClFN3
Molecular Weight	185.59 g/mol
Synonyms	6-Amino-3-chloro-4-fluoro-1H-indazole; 3-Chloro-4-fluoro-1H-indazol-6-amine; 1H-Indazole-6-amine, 3-chloro-4-fluoro-; 885520-15-0; 6-Amino-3-chloro-4-fluoroindazole; 4-Fluoro-6-amino-3-chloroindazole
EINECS	Contact for details

Quality Control

Our 6-Amino-3-Chloro-4-Fluoro (1H)Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high standards, such as pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.