Description

4-Amino-3-Hydroxy-6-Iodo-1H-Indazole is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular scaffold, featuring amino, hydroxy, and iodo substituents, makes it a versatile intermediate for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted therapeutic agents, particularly kinase inhibitors and other small-molecule drugs.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probes: Used in the development of molecular probes and labeled compounds for biochemical and cellular studies.
• Organic Synthesis Building Block: The reactive iodo and amino groups facilitate further functionalization via cross-coupling and condensation reactions.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and herbicides.

Basic Information

Product Name	4-Amino-3-Hydroxy-6-Iodo-1H-Indazole
CAS No.	885520-12-7
Molecular Formula	C7H6IN3O
Molecular Weight	275.05 g/mol
Synonyms	6-Iodo-1H-indazol-3-ol, 4-amino-; 4-Amino-6-iodo-1H-indazol-3-ol; 4-Amino-3-hydroxy-6-iodoindazole; 4-Amino-6-iodo-3-indazolol; 1H-Indazol-3-ol, 4-amino-6-iodo-; 885520-12-7; 4-Amino-3-hydroxy-6-iodo-1H-indazole; 6-Iodo-4-amino-1H-indazol-3-ol
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Hydroxy-6-Iodo-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from techniques including HPLC, NMR, and mass spectrometry. Specifications are designed to meet the stringent requirements of pharmaceutical R&D and can be aligned with current Good Manufacturing Practice (cGMP) principles for advanced intermediates upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.