Description

6-Amino-4-Fluoroindazole is a high-purity fluorinated indazole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular architecture, which combines a reactive amino group with a fluorine substituent on the indazole core, enabling precise modifications for developing novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Bioconjugation: The reactive amino group facilitates linking to biomolecules for diagnostic and research applications.
• Academic & R&D: A valuable reagent for universities and contract research organizations (CROs) exploring heterocyclic chemistry.

Basic Information

Product Name	6-Amino-4-Fluoroindazole
CAS No.	885520-07-0
Molecular Formula	C7H6FN3
Molecular Weight	151.14 g/mol
Synonyms	4-Fluoro-6-aminoindazole; 4-Fluoro-1H-indazol-6-amine; 6-Amino-4-fluoro-1H-indazole; 1H-Indazol-6-amine, 4-fluoro-; 4-Fluoro-1H-indazol-6-ylamine; 6-Amino-4-fluoroindazole; 4-Fluoroindazol-6-amine
EINECS	Contact for details

Quality Control

Our 6-Amino-4-Fluoroindazole is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.