Description

4-Amino-6-Chloro-3-(1H)Indazole Carboxylic Acid is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique indazole core functionalized with amino, chloro, and carboxylic acid groups makes it an invaluable intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Kinase Inhibitor Development: Used to construct core scaffolds for potential kinase inhibitors, a major class in oncology research.
• Agrochemical Research: Serves as a building block for developing new active ingredients in crop protection products.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes for studying enzyme function and protein interactions.
• Material Science Research: Investigated as a monomer or functional component for creating specialty polymers with unique properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical and biotech R&D pipelines.

Basic Information

Product Name	4-Amino-6-Chloro-3-(1H)Indazole Carboxylic Acid
CAS No.	885520-05-8
Molecular Formula	C8H6ClN3O2
Molecular Weight	211.61 g/mol
Synonyms	4-Amino-6-chloro-1H-indazole-3-carboxylic acid; 6-Chloro-4-amino-1H-indazole-3-carboxylic acid; 4-Amino-6-chloroindazole-3-carboxylic acid; 1H-Indazole-3-carboxylic acid, 4-amino-6-chloro-; 885520-05-8; 4-Amino-6-chloro-3-carboxyindazole; 6-Chloro-4-aminoindazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Amino-6-Chloro-3-(1H)Indazole Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results. We support cGMP-compliant production for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.