Description

4-Methoxycarbonyl-6-Nitro-(1H)Indazole Carboxaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique indazole core functionalized with aldehyde, nitro, and methoxycarbonyl groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel, targeted therapeutic agents. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs, particularly for oncology and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel indazole-based drug candidates targeting specific enzymes and receptors.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize lead compounds.
• API Development: Serves as a crucial synthon in the multi-step manufacturing process of Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	4-Methoxycarbonyl-6-Nitro-(1H)Indazole Carboxaldehyde
CAS No.	885519-80-2
Molecular Formula	C11H9N3O5
Molecular Weight	263.21 g/mol
Synonyms	6-Nitro-1H-indazole-4-carboxylic acid methyl ester-7-carboxaldehyde; Methyl 6-nitro-7-formyl-1H-indazole-4-carboxylate; 7-Formyl-6-nitro-1H-indazole-4-carboxylic acid methyl ester; 4-(Methoxycarbonyl)-6-nitro-1H-indazole-7-carbaldehyde; 6-Nitro-7-formyl-1H-indazole-4-carboxylic acid methyl ester; 4-Carbomethoxy-6-nitro-1H-indazole-7-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-Methoxycarbonyl-6-Nitro-(1H)Indazole Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere for long-term stability. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong reducing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.