Description

3-Hydroxy-6-Nitro-4-(1H)Indazole Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate with the CAS number 885519-77-7. This compound is critical for the synthesis of complex heterocyclic molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the production of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel indazole-based drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex APIs, particularly those containing the indazole core structure.
• Biochemical Research: Employed as a standard or reference compound in analytical method development and biochemical assays.
• Fine Chemical Production: An important building block for manufacturing specialized fine chemicals and custom synthesis projects.

Basic Information

Item	Detail
Product Name	3-Hydroxy-6-Nitro-4-(1H)Indazole Carboxylic Acid Methyl Ester
CAS No.	885519-77-7
Molecular Formula	C10H7N3O5
Molecular Weight	249.18 g/mol
Synonyms	Methyl 3-hydroxy-6-nitro-1H-indazole-4-carboxylate; 6-Nitro-3-hydroxy-1H-indazole-4-carboxylic acid methyl ester; 3-Hydroxy-6-nitro-1H-indazole-4-carboxylic acid methyl ester; 885519-77-7; Methyl 3-hydroxy-6-nitroindazole-4-carboxylate; 4-(Methoxycarbonyl)-6-nitro-1H-indazol-3-ol
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-6-Nitro-4-(1H)Indazole Carboxylic Acid Methyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.