Description

6-Iodo-4-Indazolecarboxylic Acid Methyl Ester is a high-purity, functionalized indazole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile synthetic intermediate, enabling the construction of complex molecular architectures through its reactive iodine and ester functional groups. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and oncology research programs.
• Agrochemical Research: Used to develop new active ingredients for crop protection products, leveraging the indazole scaffold's bioactivity.
• Chemical Biology: Serves as a probe or linker in the development of chemical tools for studying biological pathways.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Medicinal Chemistry SAR Studies: Used to explore structure-activity relationships by introducing diverse substituents at the 4- and 6- positions of the indazole core.

Basic Information

Item	Detail
Product Name	6-Iodo-4-Indazolecarboxylic Acid Methyl Ester
CAS No.	885519-74-4
Molecular Formula	C9H7IN2O2
Molecular Weight	302.07 g/mol
Synonyms	Methyl 6-Iodo-1H-indazole-4-carboxylate; 6-Iodo-1H-indazole-4-carboxylic Acid Methyl Ester; 4-Carbomethoxy-6-iodoindazole; Methyl 6-iodo-4-indazolecarboxylate; 6-Iodoindazole-4-carboxylic Acid Methyl Ester; 885519-74-4; 6-Iodo-4-indazolecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 6-Iodo-4-Indazolecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.