Description

3-Chloro-6-Nitro-4-(1H)Indazole Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is essential for research and development chemists and manufacturers in the pharmaceutical and biotechnology sectors seeking to develop new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indazole-based drug molecules for oncology and other therapeutic areas.
• Chemical Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Research & Development: Serves as a standard or starting material in academic and industrial R&D labs for novel heterocyclic compound discovery.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the multi-step synthesis of final API compounds requiring the specific indazole scaffold.
• Process Chemistry: Used in scale-up and process development for the commercial production of specialized fine chemicals.

Basic Information

Product Name	3-Chloro-6-Nitro-4-(1H)Indazole Carboxylic Acid Methyl Ester
CAS No.	885519-73-3
Molecular Formula	C9H6ClN3O4
Molecular Weight	255.62 g/mol
Synonyms	Methyl 3-chloro-6-nitro-1H-indazole-4-carboxylate; 3-Chloro-6-nitro-1H-indazole-4-carboxylic acid methyl ester; 4-(1H)-Indazolecarboxylic acid, 3-chloro-6-nitro-, methyl ester; 885519-73-3; Methyl 3-chloro-6-nitroindazole-4-carboxylate
EINECS	Contact for details

Quality Control

Our 3-Chloro-6-Nitro-4-(1H)Indazole Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee consistency and traceability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.