Description

4-Bromo-3-Iodo-6-Nitro (1H)Indazole is a high-purity, multi-halogenated indazole derivative designed for advanced pharmaceutical and agrochemical research. This compound serves as a critical synthetic intermediate, enabling the construction of complex molecular architectures through its reactive halogen sites and nitro group. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its halogenated indazole core.
• Material Science Precursor: Serves as a starting material for creating specialized organic ligands and functional polymers.
• Chemical Biology Probe Development: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Cross-Coupling Reactions: The bromo and iodo substituents make it an excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.
• Nitro Group Transformations: The nitro group can be reduced to an amine, providing a handle for further functionalization via amide coupling or reductive amination.

Basic Information

Product Name	4-Bromo-3-Iodo-6-Nitro (1H)Indazole
CAS No.	885519-55-1
Molecular Formula	C7H3BrIN3O2
Molecular Weight	367.93 g/mol
Synonyms	4-Bromo-3-iodo-6-nitro-1H-indazole; 1H-Indazole, 4-bromo-3-iodo-6-nitro-; 6-Nitro-4-bromo-3-iodo-1H-indazole; 4-Bromo-3-iodo-6-nitroindazole; 885519-55-1; 4-Br-3-I-6-NO2-indazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Iodo-6-Nitro (1H)Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from HPLC, NMR, and mass spectrometry to support your regulatory and R&D requirements. Our quality commitment ensures reliable performance in your most sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.