Description

4-Chloro-6-Nitro-1H-Indazole is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its unique indazole core, functionalized with chloro and nitro substituents, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where it serves as a key precursor for further functionalization and derivatization.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, leveraging its reactive sites for structural modification.
• Material Science Research: Serves as a building block for novel organic electronic materials, dyes, and pigments due to its electron-deficient aromatic system.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and nucleophilic substitution reactions.

Basic Information

Product Name	4-Chloro-6-Nitro-1H-Indazole
CAS No.	885519-11-9
Molecular Formula	C7H4ClN3O2
Molecular Weight	197.58 g/mol
Synonyms	4-Chloro-6-nitro-1H-indazole; 1H-Indazole, 4-chloro-6-nitro-; 4-Chloro-6-nitroindazole; 6-Nitro-4-chloro-1H-indazole; 885519-11-9; 4-Chloro-6-nitroindazol; 4-Chloro-6-nitro-1H-indazol
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Nitro-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.