Description

3-Hydroxy-6-(1H)Indazole Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate with significant synthetic utility. This compound is valued for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially those targeting kinase inhibition and other enzyme-related pathways.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing indazole-based molecular libraries and for lead optimization studies.
• Research & Development (R&D): Serves as a standard or starting material in academic and industrial research focused on heterocyclic chemistry and new chemical entity (NCE) development.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of specialized compounds on a client-specific basis.

Basic Information

Product Name	3-Hydroxy-6-(1H)Indazole Carboxylic Acid Methyl Ester
CAS No.	885518-84-3
Molecular Formula	C9H8N2O3
Molecular Weight	192.17 g/mol
Synonyms	Methyl 3-hydroxy-1H-indazole-6-carboxylate; 1H-Indazole-6-carboxylic acid, 3-hydroxy-, methyl ester; 3-Hydroxy-1H-indazole-6-carboxylic acid methyl ester; 6-(Methoxycarbonyl)-1H-indazol-3-ol; Methyl 3-hydroxyindazole-6-carboxylate
EINECS	Contact for details

Quality Control

Our production of 3-Hydroxy-6-(1H)Indazole Carboxylic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.