Description

6-Bromo-3-Cyano-4-Nitro-1H Indazole is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular scaffold, featuring bromo, cyano, and nitro substituents, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel kinase inhibitors, anticancer agents, and other biologically active small molecules.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and plant growth regulators due to its reactive halogen and nitro groups.
• Material Science Precursor: Serves as a building block for organic semiconductors, liquid crystals, and photoactive polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Nucleophilic Substitution & Reduction: The nitro and cyano groups provide handles for further functionalization through reduction to amines or conversion to other functional groups.

Basic Information

Item	Details
Product Name	6-Bromo-3-Cyano-4-Nitro-1H Indazole
CAS No.	885518-60-5
Molecular Formula	C8H3BrN4O2
Molecular Weight	267.04 g/mol
Synonyms	6-Bromo-4-nitro-1H-indazole-3-carbonitrile; 6-Bromo-3-cyano-4-nitroindazole; 1H-Indazole-3-carbonitrile, 6-bromo-4-nitro-; 885518-60-5; 6-Bromo-4-nitroindazole-3-carbonitrile; 4-Nitro-6-bromo-1H-indazole-3-carbonitrile; 6-Bromo-4-nitro-1H-indazole-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Cyano-4-Nitro-1H Indazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.