Description

1H-Indazole-6-Carboxylic Acid, 4-Bromo-3-Formyl-, Methyl Ester is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both bromo and formyl substituents on the indazole core, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and oncology research programs.
• Agrochemical Development: Serves as a building block for creating new active ingredients with potential herbicidal or fungicidal properties.
• Material Science Research: Used in the development of organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical spaces.

Basic Information

Product Name	1H-Indazole-6-Carboxylic Acid, 4-Bromo-3-Formyl-, Methyl Ester
CAS No.	885518-48-9
Molecular Formula	C10H7BrN2O3
Molecular Weight	283.08 g/mol
Synonyms	Methyl 4-Bromo-3-formyl-1H-indazole-6-carboxylate; 4-Bromo-3-formyl-1H-indazole-6-carboxylic acid methyl ester; 1H-Indazole-6-carboxylic acid, 4-bromo-3-formyl-, methyl ester; Methyl 4-bromo-3-formylindazole-6-carboxylate; 885518-48-9; 4-Bromo-3-formylindazole-6-methyl carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Indazole-6-Carboxylic Acid, 4-Bromo-3-Formyl-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and reliable supply chain integrity makes us a trusted partner for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere when appropriate for prolonged use. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.