Description

Phosphonium, [[4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(Methylsulfonyl)Amino]-5-Pyrimidinyl]Me is a high-value, organophosphorus intermediate characterized by its unique pyrimidine-based structure with fluorophenyl and methylsulfonylamino substituents. This compound is critical for facilitating advanced organic synthesis, particularly in constructing complex molecular architectures where precise functional group manipulation is required. It is primarily sought after by research institutions and pharmaceutical development teams working on novel active ingredients, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or plant growth regulators that require a fluorinated pyrimidine core.
• Ligand & Catalyst Precursor: Acts as a precursor for specialized phosphonium-based ligands or catalysts used in cross-coupling and other transition metal-catalyzed reactions.
• Material Science: Employed in the research of advanced organic electronic materials or ionic liquids due to its ionic phosphonium center and aromatic system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.

Basic Information

Product Name	Phosphonium, [[4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(Methylsulfonyl)Amino]-5-Pyrimidinyl]Me
CAS No.	885477-83-8
Molecular Formula	C21H26FN4O2PS
Molecular Weight	456.49 g/mol
Synonyms	[[4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(Methylsulfonyl)Amino]-5-Pyrimidinyl]Methyl]Triphenylphosphonium; 5-[(Triphenylphosphonio)methyl]-4-(4-fluorophenyl)-6-isopropyl-2-[(methylsulfonyl)(methyl)amino]pyrimidine; Phosphonium Salt Intermediate 885477-83-8; Fluorophenyl Isopropyl Pyrimidinyl Phosphonium Salt; Methyl(Methylsulfonyl)Amino Pyrimidine Phosphonium Derivative
EINECS	Contact for details

Quality Control

Our Phosphonium, [[4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(Methylsulfonyl)Amino]-5-Pyrimidinyl]Me is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and HPLC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.