Description

C-[2-(2-Chloro-Phenyl)-Thiazol-4-Yl]-Methylamine is a high-purity, advanced pharmaceutical intermediate featuring a functionalized thiazole core. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing targeted molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Research: Employed as a molecular probe or a tag in proteomics and bio-conjugation studies due to its reactive amine group.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers with unique electronic or optical properties.

Basic Information

Product Name	C-[2-(2-Chloro-Phenyl)-Thiazol-4-Yl]-Methylamine
CAS No.	885280-09-1
Molecular Formula	C10H9ClN2S
Molecular Weight	224.71 g/mol
Synonyms	4-Thiazolemethanamine, 2-(2-chlorophenyl)-; (2-(2-Chlorophenyl)thiazol-4-yl)methanamine; 2-(2-Chlorophenyl)-4-thiazolemethanamine; 2-(2-Chlorophenyl)-1,3-thiazol-4-ylmethanamine; 885280-09-1; C-[2-(2-Chloro-Phenyl)-Thiazol-4-Yl]-Methylamine; 4-(Aminomethyl)-2-(2-chlorophenyl)thiazole
EINECS	Contact for details

Quality Control

Our C-[2-(2-Chloro-Phenyl)-Thiazol-4-Yl]-Methylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for trace metals, residual solvents, and related substances, supporting development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.