Description

[2-(3-Fluoro-Phenyl)-Thiazol-4-Yl]-Methanol is a high-value fluorinated thiazole derivative, a crucial building block in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which combines a fluorinated aromatic ring with a thiazole heterocycle and a hydroxymethyl functional group, enabling precise structural modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially in areas like kinase inhibitors, anti-infectives, and CNS-active compounds.
• Agrochemical Research: Serves as a core structure for synthesizing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Material Science Precursor: Used in the synthesis of specialized ligands, organic semiconductors, and liquid crystals due to its conjugated system and fluorine atom.
• Chemical Biology Probe: Employed in medicinal chemistry to study protein-ligand interactions and for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	[2-(3-Fluoro-Phenyl)-Thiazol-4-Yl]-Methanol
CAS No.	885279-97-0
Molecular Formula	C10H8FNO1S
Molecular Weight	209.24 g/mol
Synonyms	4-Thiazolemethanol, 2-(3-fluorophenyl)-; (2-(3-Fluorophenyl)thiazol-4-yl)methanol; 2-(3-Fluorophenyl)-1,3-thiazol-4-ylmethanol; 2-(3-Fluorophenyl)-4-thiazolemethanol; 2-(3-Fluorophenyl)-4-hydroxymethylthiazole; 2-(m-Fluorophenyl)-4-thiazolemethanol; [2-(3-Fluorophenyl)-1,3-thiazol-4-yl]methanol
EINECS	Contact for details

Quality Control

Our [2-(3-Fluoro-Phenyl)-Thiazol-4-Yl]-Methanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please inquire.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% / ≥ 99.0% (Higher grades available)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.