Description

4-(3-Amino-Phenyl)-Thiazole-2-Carboxylic Acid Methyl Ester is a high-purity, synthetically valuable heterocyclic building block. This compound is critical for research and development in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought by pharmaceutical, agrochemical, and specialty chemical manufacturers for use as a key intermediate in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Serves as a core scaffold for developing new generations of herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Used in the research and development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated thiazole-phenyl system.
• Dye & Pigment Synthesis: Acts as an intermediate for creating specialized heterocyclic dyes and pigments with specific light-absorption properties.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalytic systems used in asymmetric synthesis.
• Chemical Biology Probes: Employed as a building block for synthesizing molecular probes to study biological pathways and protein functions.

Basic Information

Product Name	4-(3-Amino-Phenyl)-Thiazole-2-Carboxylic Acid Methyl Ester
CAS No.	885279-72-1
Molecular Formula	C11H10N2O2S
Molecular Weight	234.27 g/mol
Synonyms	Methyl 4-(3-aminophenyl)-1,3-thiazole-2-carboxylate; 4-(3-Aminophenyl)-2-thiazolecarboxylic Acid Methyl Ester; 2-Thiazolecarboxylic acid, 4-(3-aminophenyl)-, methyl ester; 4-(3-Aminophenyl)thiazole-2-carboxylic acid methyl ester; 4-(m-Aminophenyl)thiazole-2-carboxylic acid methyl ester; 885279-72-1; Methyl 4-(m-aminophenyl)thiazole-2-carboxylate
EINECS	Contact for details

Quality Control

Our 4-(3-Amino-Phenyl)-Thiazole-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.