Description

Ethyl 5,6-Difluoro-1H-Indazole-3-Carboxylate is a high-purity fluorinated indazole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for its utility in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Agrochemical Synthesis: Employed in the synthesis of novel herbicides, fungicides, and pesticides, leveraging the biological activity of the difluorinated indazole core.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale API batches.
• Academic Research: Serves as a starting material for novel heterocyclic chemistry and methodology development in university and institutional labs.

Basic Information

Product Name	Ethyl 5,6-Difluoro-1H-Indazole-3-Carboxylate
CAS No.	885279-04-9
Molecular Formula	C10H8F2N2O2
Molecular Weight	226.18 g/mol
Synonyms	5,6-Difluoro-1H-indazole-3-carboxylic acid ethyl ester; Ethyl 5,6-difluoroindazole-3-carboxylate; 1H-Indazole-3-carboxylic acid, 5,6-difluoro-, ethyl ester; 885279-04-9; 5,6-Difluoro-1H-indazole-3-carboxylic acid ethyl ester; Ethyl 5,6-difluoro-1H-indazole-3-carboxylate; 3-Carbethoxy-5,6-difluoroindazole
EINECS	Contact for details

Quality Control

Our Ethyl 5,6-Difluoro-1H-Indazole-3-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for fine chemical and pharmaceutical intermediate production, ensuring material suitability for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and stored away from direct light and moisture sources.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.