Description

Methyl 5,6-Difluoro-1H-Indazole-3-Carboxylate CAS NO 885279-01-6 is a high-purity fluorinated indazole derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in providing a versatile and functionalized scaffold for constructing complex bioactive molecules, particularly in medicinal chemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Development: Serves as a precursor for novel herbicides, fungicides, and pesticides with enhanced activity.
• Chemical Biology Probes: Utilized in the development of fluorescent or affinity probes for target identification and validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs for client-specific molecule synthesis.
• Academic Research: Employed in university and institutional labs for heterocyclic chemistry and fluorine chemistry studies.

Basic Information

Product Name	Methyl 5,6-Difluoro-1H-Indazole-3-Carboxylate
CAS No.	885279-01-6
Molecular Formula	C9H6F2N2O2
Molecular Weight	212.15 g/mol
Synonyms	5,6-Difluoro-1H-indazole-3-carboxylic acid methyl ester; Methyl 5,6-difluoroindazole-3-carboxylate; 1H-Indazole-3-carboxylic acid, 5,6-difluoro-, methyl ester; 885279-01-6; 5,6-Difluoro-1H-indazole-3-carboxylic acid methyl ester; 3-Carbomethoxy-5,6-difluoroindazole
EINECS	Contact for details

Quality Control

Our Methyl 5,6-Difluoro-1H-Indazole-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to GMP-grade standards for advanced intermediates ensures reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.