Description

Ethyl 7-Benzyloxy-1H-Indazole-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a defined benzyl-protected indazole core structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• API Development: Integral in the process development and scale-up of new active pharmaceutical ingredients, especially those containing an indazole heterocycle.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for analytical method development and validation.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs engaged in custom synthesis and process optimization for client projects.

Basic Information

Product Name	Ethyl 7-Benzyloxy-1H-Indazole-3-Carboxylate
CAS No.	885278-92-2
Molecular Formula	C17H16N2O3
Molecular Weight	296.32 g/mol
Synonyms	Ethyl 7-(benzyloxy)-1H-indazole-3-carboxylate; 7-Benzyloxy-1H-indazole-3-carboxylic Acid Ethyl Ester; 1H-Indazole-3-carboxylic acid, 7-(phenylmethoxy)-, ethyl ester; 885278-92-2; SCHEMBL2188307; ZINC000253899793; AKOS025147065; BCP31034
EINECS	Contact for details

Quality Control

Our Ethyl 7-Benzyloxy-1H-Indazole-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.