Description

2,3-Dihydro-1H-Indole-4-Carbonitrile Hydrochloride is a versatile indole-based chemical intermediate, primarily valued for its role in advanced pharmaceutical synthesis. This compound is crucial for research and development chemists seeking to construct complex heterocyclic scaffolds. It is particularly relevant for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals, serving the needs of the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with specific biological activity.
• Organic Synthesis: Serves as a versatile precursor for constructing complex indole derivatives and fused heterocyclic systems in academic and industrial R&D.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological pathway investigation.
• Material Science: Potential intermediate for the synthesis of specialty polymers and organic electronic materials.

Basic Information

Product Name	2,3-Dihydro-1H-Indole-4-Carbonitrile Hydrochloride
CAS No.	885278-80-8
Molecular Formula	C9H9ClN2
Molecular Weight	180.63 g/mol
Synonyms	4-Cyano-2,3-dihydro-1H-indole hydrochloride; 2,3-Dihydro-1H-indole-4-carbonitrile hydrochloride; 4-Cyanoindoline hydrochloride; Indoline-4-carbonitrile hydrochloride; 1H-Indole-4-carbonitrile, 2,3-dihydro-, hydrochloride (1:1); 885278-80-8; 4-CN-indoline HCl
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1H-Indole-4-Carbonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure the material meets your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.