Description

4-Benzyloxy-2,3-Dihydro-1H-Indole is a versatile indole derivative, a key heterocyclic scaffold in organic synthesis. This compound matters as a crucial synthetic intermediate for developing novel pharmaceuticals and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a core building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, serotonin receptor modulators, and other bioactive molecules.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the indole moiety's biological activity.
• Organic Synthesis Reagent: Acts as a protected indole precursor or a starting material for palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination.
• Material Science: Investigated as a monomer or functional component in the creation of specialty polymers and organic electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry to explore structure-activity relationships (SAR) and develop enzyme inhibitors or receptor ligands.
• Academic & Contract Research: Essential for university laboratories and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic chemistry.

Basic Information

Item	Details
Product Name	4-Benzyloxy-2,3-Dihydro-1H-Indole
CAS No.	885278-77-3
Molecular Formula	C15H15NO
Molecular Weight	225.29 g/mol
Synonyms	4-(Benzyloxy)-2,3-dihydro-1H-indole; 1H-Indole, 4-(phenylmethoxy)-2,3-dihydro-; 4-(Phenylmethoxy)-2,3-dihydro-1H-indole; 4-Benzyloxyindoline; Indoline, 4-benzyloxy-; 4-O-Benzylindoline
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-2,3-Dihydro-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.