Description

Methyl 5-Benzyloxy-1H-Indazole-3-Carboxylate is a high-purity, synthetically valuable indazole derivative, serving as a crucial advanced pharmaceutical intermediate. Its core value lies in providing a versatile, functionalized scaffold for the research and development of novel therapeutic agents, particularly in oncology and CNS disorders. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality building blocks for drug discovery and synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting protein kinases and other enzyme families.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Serves as a precursor for creating molecular probes to study biological pathways and target validation.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for the custom synthesis of specialized compounds for client projects.
• Library Synthesis: Utilized in combinatorial chemistry to generate diverse compound libraries for high-throughput screening.
• Process Chemistry Development: Acts as a critical intermediate in scaling up synthetic routes from laboratory to pilot and commercial production.

Basic Information

Product Name	Methyl 5-Benzyloxy-1H-Indazole-3-Carboxylate
CAS No.	885278-62-6
Molecular Formula	C16H14N2O3
Molecular Weight	282.30 g/mol
Synonyms	5-(Benzyloxy)-1H-indazole-3-carboxylic acid methyl ester; Methyl 5-(phenylmethoxy)-1H-indazole-3-carboxylate; 1H-Indazole-3-carboxylic acid, 5-(benzyloxy)-, methyl ester; 5-Benzyloxyindazole-3-carboxylic acid methyl ester; MBIC
EINECS	Contact for details

Quality Control

Our Methyl 5-Benzyloxy-1H-Indazole-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring material traceability and reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.