Description

6-Chloro-1H-Indazole-3-Carbonitrile is a versatile and high-value heterocyclic building block, specifically an indazole derivative, with the CAS registry number 885278-30-8. This compound is critical for research and development in medicinal chemistry, serving as a key precursor for synthesizing novel pharmaceutical candidates. It is primarily needed by R&D laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in drug discovery programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A crucial scaffold for the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization for developing kinase inhibitors and other targeted therapies.
• Agrochemical Development: Serves as a building block for creating novel herbicides, fungicides, and plant growth regulators.
• Material Science: Potential precursor for advanced organic materials, including ligands for catalysis and components for organic electronics.
• Biochemical Tool Compound: Used in biochemical assays to study enzyme function and cellular pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	6-Chloro-1H-Indazole-3-Carbonitrile
CAS No.	885278-30-8
Molecular Formula	C8H4ClN3
Molecular Weight	177.59 g/mol
Synonyms	6-Chloro-1H-indazole-3-carbonitrile; 6-Chloro-3-cyano-1H-indazole; 3-Cyano-6-chloro-1H-indazole; 1H-Indazole-3-carbonitrile, 6-chloro-; 885278-30-8; 6-Chloroindazole-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Chloro-1H-Indazole-3-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.