Description

6-Bromo-1H-Indazole-3-Carbonitrile is a versatile and high-value brominated indazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both bromine and nitrile functional groups, makes it an essential building block for constructing complex heterocyclic frameworks. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active small molecules targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold for designing activity-based probes and molecular tags to study enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring specialized bromo-indazole chemistry.

Basic Information

Product Name	6-Bromo-1H-Indazole-3-Carbonitrile
CAS No.	885278-24-0
Molecular Formula	C8H4BrN3
Molecular Weight	222.04 g/mol
Synonyms	6-Bromo-1H-indazole-3-carbonitrile; 6-Bromoindazole-3-carbonitrile; 3-Cyano-6-bromo-1H-indazole; 885278-24-0; 6-Bromo-1H-indazol-3-yl cyanide; 6-Bromo-3-cyano-1H-indazole; 6-Bromoindazole-3-CN
EINECS	Contact for details

Quality Control

Our production of 6-Bromo-1H-Indazole-3-Carbonitrile adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified through modern analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.