Description

(3-n-Boc-Amino-Pyrrolidin-1-Yl)-Thiophen-3-Yl-Acetic Acid is a high-purity, non-natural amino acid derivative featuring a Boc-protected pyrrolidine moiety linked to a thiophene acetic acid core. This compound is a critical pharmaceutical intermediate valued for its role in constructing complex molecular architectures for drug discovery and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the areas of protease inhibitors and other small molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially protease inhibitors and other enzyme-targeted therapies.
• Peptidomimetics Research: Used to create modified peptide structures that mimic natural peptides but with enhanced stability and bioavailability.
• Chemical Biology Probes: Serves as a scaffold for developing probes to study enzyme function and protein-protein interactions.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for the custom production of complex organic molecules.
• Library Synthesis: A valuable reagent for generating diverse compound libraries for high-throughput screening in drug discovery programs.

Basic Information

Product Name	(3-n-Boc-Amino-Pyrrolidin-1-Yl)-Thiophen-3-Yl-Acetic Acid
CAS No.	885276-40-4
Molecular Formula	C15H22N2O4S
Molecular Weight	326.41 g/mol
Synonyms	1-(1,1-Dimethylethyl) 3-[[(3-thienylacetyl)amino]-1-pyrrolidinecarboxylate; 3-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-pyrrolidinyl(3-thienyl)acetic acid; Boc-3-amino-pyrrolidine-1-thiophene-3-acetic acid; (3-(tert-Butoxycarbonylamino)pyrrolidin-1-yl)(thiophen-3-yl)acetic acid; 3-(Boc-amino)pyrrolidine thiophene-3-acetic acid; N-Boc-3-aminopyrrolidine thiophene-3-acetic acid derivative
EINECS	Contact for details

Quality Control

Our (3-n-Boc-Amino-Pyrrolidin-1-Yl)-Thiophen-3-Yl-Acetic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support GMP-grade production requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.