Description

(3-Boc-Amino-Pyrrolidin-1-Yl)-(1H-Indol-2-Yl)-Acetic Acid CAS NO 885276-31-3 is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold that combines a protected pyrrolidine amine with an indole acetic acid moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting G-protein-coupled receptors (GPCRs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: The molecular structure is suitable for creating inhibitors for various enzymatic targets.
• Peptidomimetic Synthesis: Serves as a non-peptide backbone mimic for developing metabolically stable bioactive compounds.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis Building Block: Supplied to contract research organizations (CROs) and CDMOs for custom synthesis projects.

Basic Information

Product Name	(3-Boc-Amino-Pyrrolidin-1-Yl)-(1H-Indol-2-Yl)-Acetic Acid
CAS No.	885276-31-3
Molecular Formula	C19H25N3O4
Molecular Weight	359.42 g/mol
Synonyms	1-(1,1-Dimethylethyl) 2-[(3-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-pyrrolidinyl]-1H-indole-2-acetate; 2-[(3-[(tert-Butoxycarbonyl)amino]-1-pyrrolidinyl](1H-indol-2-yl)acetic acid; tert-Butyl N-[1-[2-(1H-indol-2-yl)-2-oxoethyl]pyrrolidin-3-yl]carbamate; Boc-3-amino-pyrrolidine-indole-2-acetic acid; (3-Boc-aminopyrrolidin-1-yl)-(1H-indol-2-yl)acetic acid; (3-((tert-Butoxycarbonyl)amino)pyrrolidin-1-yl)(1H-indol-2-yl)acetic acid
EINECS	Contact for details

Quality Control

Our (3-Boc-Amino-Pyrrolidin-1-Yl)-(1H-Indol-2-Yl)-Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.