Description

(3-Boc-Amino-Pyrrolidin-1-Yl)-Thiophen-2-Yl-Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold combining a protected pyrrolidine amine with a thiophene acetic acid moiety. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with potential therapeutic activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting protease inhibitors and GPCR modulators.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its versatile chemical handles.
• Peptidomimetic Synthesis: The Boc-protected amine and acetic acid group make it valuable for constructing non-peptide scaffolds that mimic peptide structures.
• Chemical Biology Probes: Employed in the development of tool compounds and molecular probes for investigating biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of clinical trial materials.

Basic Information

Item	Details
Product Name	(3-Boc-Amino-Pyrrolidin-1-Yl)-Thiophen-2-Yl-Acetic Acid
CAS No.	885276-25-5
Molecular Formula	C15H22N2O4S
Molecular Weight	326.41 g/mol
Synonyms	2-[(3-[(tert-Butoxycarbonyl)amino]-1-pyrrolidinyl]-2-thienylacetic Acid; 2-(3-((tert-Butoxycarbonyl)amino)pyrrolidin-1-yl)-2-(thiophen-2-yl)acetic Acid; (3-Boc-Aminopyrrolidin-1-yl)(2-thienyl)acetic Acid; 2-(3-Boc-aminopyrrolidin-1-yl)-2-thiophen-2-yl-acetic acid; 885276-25-5; tert-Butyl N-[1-[2-carboxy-2-(thiophen-2-yl)ethyl]pyrrolidin-3-yl]carbamate
EINECS	Contact for details

Quality Control

Our (3-Boc-Amino-Pyrrolidin-1-Yl)-Thiophen-2-Yl-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.