Description

(3-Boc-Amino-Azetidin-1-Yl)-(1H-Indol-2-Yl)-Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold combining an azetidine ring and an indole moiety. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting various therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new drug candidates, especially within oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Protease Inhibitor Development: Serves as a core scaffold in the design of inhibitors for various enzymatic targets.
• Kinase Inhibitor Synthesis: Employed in the construction of potential kinase inhibitors for oncology applications.
• Peptidomimetic Chemistry: Utilized to create constrained analogs of peptide structures to enhance metabolic stability.
• Chemical Biology Probes: Acts as a starting material for developing tool compounds to study biological pathways.

Basic Information

Product Name	(3-Boc-Amino-Azetidin-1-Yl)-(1H-Indol-2-Yl)-Acetic Acid
CAS No.	885276-02-8
Molecular Formula	C18H23N3O4
Molecular Weight	345.40 g/mol
Synonyms	1-(1H-Indol-2-yl)-2-[3-[(tert-butoxycarbonyl)amino]azetidin-1-yl]-2-oxoacetic acid; 2-(3-((tert-Butoxycarbonyl)amino)azetidin-1-yl)-2-(1H-indol-2-yl)acetic acid; (3-((tert-Butoxycarbonyl)amino)azetidin-1-yl)(1H-indol-2-yl)acetic acid; 1H-Indole-2-acetic acid, α-[3-[[(1,1-dimethylethoxy)carbonyl]amino]-1-azetidinyl]-; Boc-Azetidine-Indole-Acetic Acid; BOC-3-Aminoazetidine-Indole-2-Acetic Acid
EINECS	Contact for details

Quality Control

Our (3-Boc-Amino-Azetidin-1-Yl)-(1H-Indol-2-Yl)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.