Description

(3-Boc-Amino-Piperidin-1-Yl)-Thiophen-3-Yl-Acetic Acid CAS NO 885275-61-6 is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core protected by a tert-butyloxycarbonyl (Boc) group and a thiophene acetic acid moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of therapeutic agents, particularly in the areas of central nervous system (CNS) and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting G-protein coupled receptors (GPCRs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• Protease Inhibitor Development: Serves as a precursor in the creation of inhibitors for various enzymatic targets.
• Peptidomimetic Synthesis: Integral component for constructing non-peptide scaffolds that mimic peptide structures.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CRMOs) for client-specific molecule assembly.

Basic Information

Product Name	(3-Boc-Amino-Piperidin-1-Yl)-Thiophen-3-Yl-Acetic Acid
CAS No.	885275-61-6
Molecular Formula	C16H24N2O4S
Molecular Weight	340.44 g/mol
Synonyms	1-(1,1-Dimethylethyl) 3-[[(3-thienylacetyl)amino]-1-piperidinecarboxylate; 3-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-piperidinyl(3-thienyl)acetate; tert-Butyl 3-[(3-thiophen-3-ylacetyl)amino]piperidine-1-carboxylate; 3-(Boc-amino)piperidin-1-yl(3-thienyl)acetic acid; Boc-3-amino-1-piperidinyl(3-thienyl)acetate; (3-Boc-Aminopiperidin-1-yl)(thiophen-3-yl)acetic acid; 885275-61-6
EINECS	Contact for details

Quality Control

Our (3-Boc-Amino-Piperidin-1-Yl)-Thiophen-3-Yl-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research and development grade standards. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.