Description

(4-Boc-Amino-Piperidin-1-Yl)-Thiophen-2-Yl-Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core protected by a tert-butoxycarbonyl (Boc) group and a thiophene acetic acid moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting therapeutic areas such as central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting protease inhibition and receptor modulation.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Peptidomimetic Synthesis: The Boc-protected piperidine structure is valuable for creating peptide-like molecules with enhanced metabolic stability.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Library Synthesis: Used in parallel and combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	(4-Boc-Amino-Piperidin-1-Yl)-Thiophen-2-Yl-Acetic Acid
CAS No.	885275-38-7
Molecular Formula	C16H24N2O4S
Molecular Weight	340.44 g/mol
Synonyms	1-(2-Carboxymethylthiophen-3-yl)-4-(tert-butoxycarbonylamino)piperidine; 4-[(tert-Butoxycarbonyl)amino]-1-(2-thienylacetyl)piperidine; 2-{3-[4-[(tert-Butoxycarbonyl)amino]-1-piperidinyl]-2-thienyl}acetic Acid; (4-Boc-Amino-Piperidin-1-Yl)-Thiophen-2-Yl-Acetic Acid; 4-(Boc-amino)-1-(2-thienylacetyl)piperidine; 4-(tert-Butoxycarbonylamino)-1-(thiophen-2-ylacetyl)piperidine; BOC-4-Amino-1-(2-thienylacetyl)piperidine; 885275-38-7
EINECS	Contact for details

Quality Control

Our (4-Boc-Amino-Piperidin-1-Yl)-Thiophen-2-Yl-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.