Description

7-Ethoxycarbonylamino-1-Oxo-1,2,3,4-Tetrahydro-Isoquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its specific isoquinoline backbone. This compound is of critical importance for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in developing new drug candidates, especially those targeting central nervous system (CNS) disorders and other specialized therapeutic applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, particularly those with isoquinoline-based structures.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• API Synthesis: Serves as a key building block in the production of Active Pharmaceutical Ingredients (APIs) for potential neurological and psychiatric treatments.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Utilized in route scouting and optimization for scalable, cost-effective manufacturing processes.

Basic Information

Product Name	7-Ethoxycarbonylamino-1-Oxo-1,2,3,4-Tetrahydro-Isoquinoline
CAS No.	885273-79-0
Molecular Formula	C₁₃H₁₄N₂O₃
Molecular Weight	246.26 g/mol
Synonyms	Ethyl 1-oxo-1,2,3,4-tetrahydroisoquinolin-7-ylcarbamate; 7-(Ethoxycarbonylamino)-3,4-dihydro-1H-isoquinolin-1-one; 7-(Ethoxycarbonylamino)-1-oxo-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-1-oxo-7-isoquinolinecarboxylic acid ethyl ester; 7-Carbamoyl-1-oxo-1,2,3,4-tetrahydroisoquinoline ethyl ester; CAS 885273-79-0
EINECS	Contact for details

Quality Control

Our 7-Ethoxycarbonylamino-1-Oxo-1,2,3,4-Tetrahydro-Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.