Description

1-Oxo-1,2,3,4-Tetrahydro-Isoquinoline-7-Sulfonic Acid Amide is a high-purity, advanced pharmaceutical intermediate with a sulfonamide functional group. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing isoquinoline-based molecular libraries for high-throughput screening (HTS).
• Research & Development (R&D): Employed in academic and industrial R&D settings for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the development pathway of new APIs requiring the 1,2,3,4-tetrahydroisoquinoline pharmacophore.

Basic Information

Product Name	1-Oxo-1,2,3,4-Tetrahydro-Isoquinoline-7-Sulfonic Acid Amide
CAS No.	885273-77-8
Molecular Formula	C9H10N2O3S
Molecular Weight	226.25 g/mol
Synonyms	7-Sulfamoyl-3,4-dihydro-1H-isoquinolin-1-one; 1,2,3,4-Tetrahydro-1-oxo-7-isoquinolinesulfonamide; 7-Aminosulfonyl-3,4-dihydroisoquinolin-1(2H)-one; 1-Oxo-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide; 7-Sulfamoyl-1,2,3,4-tetrahydroisoquinolin-1-one; 1,2,3,4-Tetrahydroisoquinoline-1-one-7-sulfonamide; Isoquinoline-7-sulfonic acid amide, 1,2,3,4-tetrahydro-1-oxo-
EINECS	Contact for details

Quality Control

Our 1-Oxo-1,2,3,4-Tetrahydro-Isoquinoline-7-Sulfonic Acid Amide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.