Description

Methyl 3-(2-Carboxy-Vinyl)-5-Methoxy-1H-Indole-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole-based molecular structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Employed in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs), particularly those with indole or tryptophan-like cores.
• Biochemical Research: Serves as a reagent for studying enzyme interactions or as a standard in analytical method development for related compounds.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.

Basic Information

Product Name	Methyl 3-(2-Carboxy-Vinyl)-5-Methoxy-1H-Indole-2-Carboxylate
CAS No.	885273-71-2
Molecular Formula	C14H13NO5
Molecular Weight	275.26 g/mol
Synonyms	Methyl (2E)-3-(5-Methoxy-2-(methoxycarbonyl)-1H-indol-3-yl)acrylate; (2E)-3-(5-Methoxy-2-(methoxycarbonyl)-1H-indol-3-yl)acrylic acid methyl ester; 5-Methoxy-3-(2-methoxy-2-oxoethenyl)-1H-indole-2-carboxylic acid methyl ester; Methyl 3-(2-carboxyethenyl)-5-methoxy-1H-indole-2-carboxylate; 3-(2-Carboxyvinyl)-5-methoxy-1H-indole-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(2-Carboxy-Vinyl)-5-Methoxy-1H-Indole-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.