Description

Ethyl 3-(2-Carboxy-Vinyl)-5-Chloro-1H-Indole-2-Carboxylate is a high-purity, multi-functional indole derivative serving as a critical advanced intermediate in modern organic synthesis. Its core value lies in providing a versatile scaffold for constructing complex heterocyclic molecules, enabling precise chemical modifications for research and development. This compound is essential for pharmaceutical chemists and agrochemical researchers engaged in the development of novel active ingredients, particularly in the areas of medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging its chlorinated indole core for bioactive molecule design.
• Organic Synthesis Reagent: Serves as a versatile precursor for synthesizing complex heterocycles, including fused indole systems and other nitrogen-containing compounds.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers and organic electronic materials.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	Ethyl 3-(2-Carboxy-Vinyl)-5-Chloro-1H-Indole-2-Carboxylate
CAS No.	885273-63-2
Molecular Formula	C₁₄H₁₂ClNO₄
Molecular Weight	293.70 g/mol
Synonyms	5-Chloro-3-(2-carboxyethenyl)-1H-indole-2-carboxylic acid ethyl ester; Ethyl 5-chloro-3-[(1E)-2-carboxyethenyl]-1H-indole-2-carboxylate; 5-Chloro-3-[(1E)-2-carboxyvinyl]-1H-indole-2-carboxylic Acid Ethyl Ester; (E)-Ethyl 3-(2-carboxyvinyl)-5-chloro-1H-indole-2-carboxylate; 2-Carboxyvinyl-5-chloroindole-2-carboxylate ethyl ester; 885273-63-2; 5-Chloro-3-(2-carboxyvinyl)-1H-indole-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-(2-Carboxy-Vinyl)-5-Chloro-1H-Indole-2-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.