Description

Ethyl 5-Bromo-3-(2-Carboxy-Vinyl)-1H-Indole-2-Carboxylate is a high-purity, multi-functional indole derivative serving as a critical advanced intermediate in modern organic synthesis. Its molecular architecture, featuring both bromo and vinyl carboxylic acid functionalities, makes it a versatile building block for constructing complex heterocyclic systems. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex indole-based drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators with novel modes of action.
• Material Science: Used in the research of organic semiconductors and functional polymers due to its conjugated vinylcarboxylic acid moiety.
• Chemical Biology: Serves as a probe or linker molecule in bioconjugation and the development of chemical tools for biological studies.
• Academic & Contract Research: Essential reagent for methodological development in organic chemistry, including cross-coupling and cyclization reactions.

Basic Information

Product Name	Ethyl 5-Bromo-3-(2-Carboxy-Vinyl)-1H-Indole-2-Carboxylate
CAS No.	885273-61-0
Molecular Formula	C14H12BrNO4
Molecular Weight	338.16 g/mol
Synonyms	5-Bromo-3-(2-carboxyethenyl)-1H-indole-2-carboxylic acid ethyl ester; Ethyl 5-bromo-3-[(1E)-2-carboxyethenyl]-1H-indole-2-carboxylate; 5-Bromo-3-(2-carboxyvinyl)-1H-indole-2-carboxylic Acid Ethyl Ester; 1H-Indole-2-carboxylic acid, 5-bromo-3-(2-carboxyethenyl)-, ethyl ester; (E)-Ethyl 5-bromo-3-(2-carboxyvinyl)-1H-indole-2-carboxylate; 885273-61-0; AI3-52762
EINECS	Contact for details

Quality Control

Our production of Ethyl 5-Bromo-3-(2-Carboxy-Vinyl)-1H-Indole-2-Carboxylate adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Every lot is fully characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.