Description

Methyl 3-Formyl-5-Methoxy-1H-Indole-2-Carboxylate is a high-purity, multi-functional indole derivative serving as a critical advanced intermediate in organic synthesis. Its unique molecular structure, featuring both formyl and methoxy substituents, makes it an exceptionally versatile building block for constructing complex heterocyclic systems. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents, anti-inflammatory compounds, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors, fluorescent dyes, and photoresponsive polymers.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including palladium-catalyzed cross-coupling reactions and multi-component syntheses.
• Bioconjugation Chemistry: The formyl group provides a handle for site-specific bioconjugation, useful in probe and linker development for biochemical applications.

Basic Information

Product Name	Methyl 3-Formyl-5-Methoxy-1H-Indole-2-Carboxylate
CAS No.	885273-51-8
Molecular Formula	C12H11NO4
Molecular Weight	233.22 g/mol
Synonyms	Methyl 5-methoxy-3-formyl-1H-indole-2-carboxylate; 5-Methoxy-3-formyl-1H-indole-2-carboxylic acid methyl ester; 1H-Indole-2-carboxylic acid, 3-formyl-5-methoxy-, methyl ester; 3-Formyl-5-methoxyindole-2-carboxylic acid methyl ester; Methyl 3-formyl-5-methoxyindole-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Formyl-5-Methoxy-1H-Indole-2-Carboxylate is manufactured and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and advanced synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.