Description

6-(3,6-Dihydro-2H-Pyran-4-Yl)-1H-Indole is a high-value heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because its unique fused indole-dihydropyran structure serves as a versatile scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used as a building block for developing new active ingredients with potential herbicidal, fungicidal, or insecticidal properties.
• Material Science: Serves as a monomer or functional unit in the development of advanced organic electronic materials, such as organic semiconductors or light-emitting diodes (OLEDs).
• Chemical Biology & Proteomics: Employed as a molecular probe or tag due to the reactivity of the indole moiety, useful for studying protein interactions and enzyme mechanisms.
• Catalyst Ligand Synthesis: The nitrogen and oxygen heteroatoms make it a candidate for constructing novel chiral or non-chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: Essential for academic institutions and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	6-(3,6-Dihydro-2H-Pyran-4-Yl)-1H-Indole
CAS No.	885273-45-0
Molecular Formula	C13H13NO
Molecular Weight	199.25 g/mol
Synonyms	6-(3,6-Dihydro-2H-pyran-4-yl)-1H-indole; 1H-Indole, 6-(3,6-dihydro-2H-pyran-4-yl)-; 6-(3,6-Dihydro-2H-pyran-4-yl)indole; 4-(1H-Indol-6-yl)-3,6-dihydro-2H-pyran; 6-(3,6-Dihydro-2H-pyran-4-yl)-1H-indole; 6-(3,6-Dihydro-2H-pyran-4-yl)indole; 6-(3,6-Dihydro-2H-pyran-4-yl)-1H-indole (CAS 885273-45-0)
EINECS	Contact for details

Quality Control

Our 6-(3,6-Dihydro-2H-Pyran-4-Yl)-1H-Indole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry for comprehensive characterization. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.