Description

5-(Tetrahydro-Thiopyran-4-Yl)-1H-Indole is a high-purity, advanced pharmaceutical intermediate featuring a unique indole scaffold fused with a saturated thiopyran moiety. This molecular architecture is critical for imparting specific biological activity and physicochemical properties in drug discovery and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly within medicinal chemistry programs targeting central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Chemical Biology Probes: Acts as a core scaffold for developing molecular probes to study enzyme and receptor functions.
• Organic Synthesis: Employed in complex multi-step syntheses requiring a functionalized indole derivative with a tetrahydrothiopyran group.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection.
• Material Science: Investigated as a precursor for specialty chemicals and functional materials.

Basic Information

Product Name	5-(Tetrahydro-Thiopyran-4-Yl)-1H-Indole
CAS No.	885273-39-2
Molecular Formula	C13H15NS
Molecular Weight	217.33 g/mol
Synonyms	5-(Tetrahydro-2H-thiopyran-4-yl)-1H-indole; 5-(Tetrahydro-4H-thiopyran-4-yl)indole; 5-(Thian-4-yl)-1H-indole; 5-(Tetrahydrothiopyran-4-yl)indole; 5-(4-Thiacyclohexyl)indole; 1H-Indole, 5-(tetrahydro-4H-thiopyran-4-yl)-; 885273-39-2
EINECS	Contact for details

Quality Control

Our 5-(Tetrahydro-Thiopyran-4-Yl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from advanced techniques like HPLC, GC, NMR, and MS. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.