Description

6-(Tetrahydro-Pyran-4-Yl)-1H-Indole is a high-purity, advanced pharmaceutical intermediate featuring a fused indole and tetrahydropyran scaffold. This compound is valued for its role as a critical building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. It is essential for pharmaceutical companies and research institutions focused on developing new therapeutic agents, especially in areas like kinase inhibitors and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the creation of novel chemical libraries for high-throughput screening.
• Kinase Inhibitor Development: Used in the research and synthesis of potential kinase inhibitors due to the privileged indole structure.
• CNS Drug Discovery: Employed in the development of compounds targeting neurological disorders, where the tetrahydropyran moiety can influence pharmacokinetic properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental organic synthesis and pharmacological studies.

Basic Information

Product Name	6-(Tetrahydro-Pyran-4-Yl)-1H-Indole
CAS No.	885273-37-0
Molecular Formula	C13H15NO
Molecular Weight	201.27 g/mol
Synonyms	6-(Tetrahydro-2H-pyran-4-yl)-1H-indole; 6-(Oxan-4-yl)-1H-indole; 6-(Tetrahydropyran-4-yl)indole; 1H-Indole, 6-(tetrahydro-4H-pyran-4-yl)-; 6-(Tetrahydro-4H-pyran-4-yl)-1H-indole; 6-(4-Tetrahydropyranyl)indole; 885273-37-0
EINECS	Contact for details

Quality Control

Our 6-(Tetrahydro-Pyran-4-Yl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP guidelines for advanced pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.